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The volume of variants in ClinVar for this gene, together with smaller sized variants inside the gene and bigger CNVs that overlap or absolutely have the gene.

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The publishing Group for this submitted (SCV) file. This column also contains the SCV accession and Edition number, the day this SCV initially appeared in ClinVar, plus the date this SCV was very last up to date in ClinVar.

03%). This variant has not been reported during the literature in people today influenced with GAA-connected circumstances. ClinVar consists of an entry for this variant (Variation ID: 574387). Variants that disrupt the consensus splice site are a comparatively prevalent reason behind aberrant splicing (PMID: 17576681, 9536098). Algorithms produced to forecast the influence of sequence adjustments on RNA splicing suggest this variant could create or improve a splice web site. In summary, the accessible proof is presently inadequate to determine the purpose of this variant in disorder. Consequently, it has been labeled as being a Variant of Unsure Importance. OK

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The global minor allele frequency calculated through the one thousand Genomes Undertaking. The insignificant allele at this area is indicated in parentheses and should be distinctive from your allele represented by this VCV report.

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